Risk of Arthritis increased with Serious Infantile infections »

New research from Sweden, to be published in the Annals of Rheumatic disease, has found that children in their first year of life who develop serious infections have an increased risk of developing arthritis. The study followed the health of 3500 people born from 1973 to 2002.
If a child is sick enough to get admitted to a hospital, they roughly double their risk of developing rheumatoid arthritis as an adult, as well as juvenile idiopathic arthritis which only affects young children and teens. There is an even greater chance of developing one subtype of rheumatoid arthritis.
Keep in mind that this increased risk is greater than other childhood causes of increased risk of arthritis including low birth weight, longer than normal pregnancy, premature delivery, high birth weight, childhood living conditions, and girls who are exposed to maternal smoking during pregnancy.
So should you change anything with regard to infection prevention and treatment in your children? While normal hygiene, including regular hand washing is recommended, parents should be more vigilant about infections in their children and if they seem to be rapidly worsening or fail to get better, they should consult their physicians to prevent worsening to the point of needing hospitalization.
There are however, plenty of other studies, for instance a German study published in the British Medical Journal in 2001 that showed that normal mild viral childhood infections, not including lower respiratory infections, actually help mature the immune system and prevent childhood asthma as well as other atopic diseases.
This Swedish study is just one more study that indirectly supports vaccination in children since the diseases we vaccinate against can be severe enough to require hospital admission, and thus gives your child an increased risk of developing arthritis later on.
Other References:
1) Illi, S, et al. Early childhood infectious diseases and the development of asthma up to school age: a birth cohort study.BMJ 2001;322:376-377 ( 17 February )
2) Hopkin JM. Early life receipt of antibiotics and atopic disorder. Clin Exp Allergy 1999; 29: 733-734



